In this article, we’ll discuss what causes leg cramps at night, how to treat them, and what other steps you can take to better manage them. Vitamin E was not effective in reducing leg cramp frequency, severity, or sleep disturbance.Ĭonclusions.- Quinine sulfate, but not vitamin E, is superior to placebo in the treatment of nocturnal leg cramps. Some medications may be able to help, and other supportive options such as massages and sports drinks are also available. There was evidence of a mild increase in side effects while subjects received quinine. Thirteen of 27 patients had at least a 50% reduction in the number of cramps while receiving quinine the response was usually seen within 3 days. Results.- Compared with treatment with placebo, quinine reduced the frequency of cramps and sleep disturbance, but not the average cramp severity. Quinine sulfate has been prescribed for decades for the treatment of nocturnal leg cramps, but clinical trials have only recently been performed. Outcome Measures.- Patients reported cramp frequency, severity, and sleep disturbance caused by cramps. These periods were separated by 4-week washout intervals. The recurrent, painful tightening usually occurs in the calf muscles and can cause severe insomnia. Intervention.- Subjects received, in random order, quinine sulfate (200 mg at supper and 300 mg at bedtime), vitamin E (800 U at bedtime), or placebo for 4-week periods. Up to 60 percent of adults report that they have had nocturnal leg cramps.
Fifty-five subjects were contacted, 30 were enrolled consecutively, and 27 completed the study. Heat is a better choice if you happen to get a. Factors that may lead to leg cramps attacks include hemodialysis, electrolyte imbalance, metabolic disorders, and congenital disorders (4). Ice works best to relax the muscle and slow down inflammation. Bedtime prep Finally, there are some bedtime things you can make part of your nighttime routine to help prevent leg cramps since they’re most likely to occur at night. Symptoms result from involuntary muscle contractions, which are sudden in onset, usually affecting the calf or foot. Apply either ice or heat to the cramped area.
Participants.- Twenty-seven male veterans, aged 38 to 73 years, who experienced at least six leg cramps per month were recruited through the general medicine walk-in clinic or were referred from other clinics. INTRODUCTION Nocturnal leg cramps, also termed sleep-related leg cramps, are a common lower-extremity condition that produces pain and can disrupt sleep. TREATMENT AND PREVENTION Try getting some mild exercise late in the day, such as a short walk, a non-strenuous bike ride or a few leg exercises. Setting.- The study was conducted at the Veterans Affairs Medical Center, White River Junction, Vt. Your care team should help you correct any dehydration or electrolyte imbalance, which may include supplements.
NOCTURNAL LEG CRAMPS TREATMENT TRIAL
Objective.- This study compared the efficacy and safety of quinine sulfate, vitamin E, and placebo in the treatment of nocturnal leg cramps.ĭesign.- A random-order, double-blind, placebocontrolled crossover trial was performed. Temperature changes Pinched nerve or spinal cord injury that compresses the nerves Lack of blood to the muscles Pregnancy Dialysis 9 tips to help deal with and prevent leg cramps Make sure you’re well-hydrated.
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